Probiotics and Cancer
05/2012
The role of Probiotics and Cancer is foundational for Immune System vitality and absorption of your nutrients. Most people do not make the connection between their digestive system and overall health.
Let’s start with some basics. We have all experienced the effects of a toilet backing up because of a clog of toilet paper or too much “you know what”…the stench and the disgusting cleanup is no fun.
Your colon is no different. Your colon is like a sewer system and is designed to expel the waste matter from food and other metabolic processes. If you do not have a healthy flora full of happy probiotics, your “sewer system” is backing up into your body. What should be coming out, gets re-absorbed as it pushes through the intestinal wall and re-circulates into the blood stream…..gross! As the body becomes increasingly toxic, proper oxidation cannot take place on a cellular level. Without proper oxygen and with a plethora of toxic materials, the cells become stressed and your Immune System becomes compromised.
The lining of your GI tract has more surface area than your external skin. There are over a billion nerve endings in the lining of your intestines. It interacts with over 20 hormones and it contains 70% to 80% of your body’s immune cells. Healthy gut = healthy body.
What is the role of Probiotics in Cancer prevention?
Probiotics literally means “for life”. In scientific terms, probiotics are live, healthy bacteria that protect your digestive system from unhealthy bacteria, viruses and parasites.
As far back as the early 1900’s, a Russian scientist suggested that disease and the aging process came as a result of “auto-intoxication” due to unhealthy bacteria producing phenols, indols and ammonia in the gut. Improving the gut flora with fermented foods that contained “lactic acid” bacteria seemed to have many health benefits.
Finally by 1989, the Journal of Applied Bacteriology stated, “There is good evidence that the complex microbial flora present in the gastrointestinal tract of all warm-blooded animals is effective in providing resistance to disease.
Probiotics play an important in the healing and prevention of Breast Cancer.
For thousands of years, fermented foods have been a part of many cultures. The Mediterranean and Middle Eastern diets have credited the relatively low rates of chronic degenerative diseases to the daily use of fermented milk and vegetable products. The Asian culture also included high probiotic fermented foods like miso and tempeh in their daily eating.
Probiotics work on several levels:
1. They fight off unhealthy organisms and reduce the risk of infection
2. They regulate Immune responses
3. They help fight inflammatory responses and reduce your risk of cancer
4. They support the healthy function of elimination form the colon.
5. They even have an effect on allergies and obesity.
The application of probiotic fermented milks in cancer and intestinal inflammation
21–24 October 2009, The 3rd International Immunonutrition Workshop, Platja D'Aro, Girona, Spain.
Alejandra de Moreno de LeBlanca1 and Gabriela Perdigóna1a2 c1
a1 Centro de Referencia para Lactobacilos (CERELA-CONICET), Chacabuco 145, Tucumán (T4000ILC), Argentina
a2 Cátedra de Inmunología, Facultad de Bioquimíca, Química y Farmacia, Universidad Nacional de Tucumán, Tucumán, Argentina
Abstract
Lactic acid bacteria are present in many foods such as yoghurt and are frequently used as probiotics to improve some biological functions of the host. Many researchers have evaluated the effects of yoghurt and lactic acid bacteria against diseases such as cancer and intestinal inflammation. The preventive effect of probiotics on intestinal carcinogenesis may be associated with changes in the intestinal microbiota, suppressing the growth of bacteria that convert procarcinogens into carcinogens. Other mechanisms could be related to the immune response modulation and have been evaluated using milks fermented with lactic acid bacteria in chemically induced colon cancer and hormone-dependent breast cancer models. We demonstrated, using a murine colon cancer model, that yoghurt consumption inhibited tumour growth by decreasing the inflammatory response by increasing IL-10-secreting cells, cellular apoptosis and diminishing procarcinogenic enzymes. Milk fermented with Lactobacillus helveticus R389 delayed breast tumour growth by decreasing IL-6 and increasing IL-10 in serum and in the mammary glands and tumour-infiltrating immune cells. Previous results obtained with yoghurt administration in a colon cancer model led us to analyse its effect on a trinitrobenzenesulfonic acid-induced intestinal inflammation model in mice. Yoghurt was able to attenuate the symptoms of acute inflammation by reducing inflammatory cytokines, and increasing regulatory cytokine IL-10-producing cells, leading to desirable changes of the intestinal microbiota. It was demonstrated, by using murine models, that the consumption of fermented milks can modulate the immune system and can maintain it in a state of surveillance, which could affront different pathologies such as cancer and intestinal inflammation.
(Online publication June 16 2010)
http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=7837748
The role of Probiotics and Cancer is foundational for Immune System vitality and absorption of your nutrients. Most people do not make the connection between their digestive system and overall health.
Let’s start with some basics. We have all experienced the effects of a toilet backing up because of a clog of toilet paper or too much “you know what”…the stench and the disgusting cleanup is no fun.
Your colon is no different. Your colon is like a sewer system and is designed to expel the waste matter from food and other metabolic processes. If you do not have a healthy flora full of happy probiotics, your “sewer system” is backing up into your body. What should be coming out, gets re-absorbed as it pushes through the intestinal wall and re-circulates into the blood stream…..gross! As the body becomes increasingly toxic, proper oxidation cannot take place on a cellular level. Without proper oxygen and with a plethora of toxic materials, the cells become stressed and your Immune System becomes compromised.
The lining of your GI tract has more surface area than your external skin. There are over a billion nerve endings in the lining of your intestines. It interacts with over 20 hormones and it contains 70% to 80% of your body’s immune cells. Healthy gut = healthy body.
What is the role of Probiotics in Cancer prevention?
Probiotics literally means “for life”. In scientific terms, probiotics are live, healthy bacteria that protect your digestive system from unhealthy bacteria, viruses and parasites.
As far back as the early 1900’s, a Russian scientist suggested that disease and the aging process came as a result of “auto-intoxication” due to unhealthy bacteria producing phenols, indols and ammonia in the gut. Improving the gut flora with fermented foods that contained “lactic acid” bacteria seemed to have many health benefits.
Finally by 1989, the Journal of Applied Bacteriology stated, “There is good evidence that the complex microbial flora present in the gastrointestinal tract of all warm-blooded animals is effective in providing resistance to disease.
Probiotics play an important in the healing and prevention of Breast Cancer.
For thousands of years, fermented foods have been a part of many cultures. The Mediterranean and Middle Eastern diets have credited the relatively low rates of chronic degenerative diseases to the daily use of fermented milk and vegetable products. The Asian culture also included high probiotic fermented foods like miso and tempeh in their daily eating.
Probiotics work on several levels:
1. They fight off unhealthy organisms and reduce the risk of infection
2. They regulate Immune responses
3. They help fight inflammatory responses and reduce your risk of cancer
4. They support the healthy function of elimination form the colon.
5. They even have an effect on allergies and obesity.
The application of probiotic fermented milks in cancer and intestinal inflammation
21–24 October 2009, The 3rd International Immunonutrition Workshop, Platja D'Aro, Girona, Spain.
Alejandra de Moreno de LeBlanca1 and Gabriela Perdigóna1a2 c1
a1 Centro de Referencia para Lactobacilos (CERELA-CONICET), Chacabuco 145, Tucumán (T4000ILC), Argentina
a2 Cátedra de Inmunología, Facultad de Bioquimíca, Química y Farmacia, Universidad Nacional de Tucumán, Tucumán, Argentina
Abstract
Lactic acid bacteria are present in many foods such as yoghurt and are frequently used as probiotics to improve some biological functions of the host. Many researchers have evaluated the effects of yoghurt and lactic acid bacteria against diseases such as cancer and intestinal inflammation. The preventive effect of probiotics on intestinal carcinogenesis may be associated with changes in the intestinal microbiota, suppressing the growth of bacteria that convert procarcinogens into carcinogens. Other mechanisms could be related to the immune response modulation and have been evaluated using milks fermented with lactic acid bacteria in chemically induced colon cancer and hormone-dependent breast cancer models. We demonstrated, using a murine colon cancer model, that yoghurt consumption inhibited tumour growth by decreasing the inflammatory response by increasing IL-10-secreting cells, cellular apoptosis and diminishing procarcinogenic enzymes. Milk fermented with Lactobacillus helveticus R389 delayed breast tumour growth by decreasing IL-6 and increasing IL-10 in serum and in the mammary glands and tumour-infiltrating immune cells. Previous results obtained with yoghurt administration in a colon cancer model led us to analyse its effect on a trinitrobenzenesulfonic acid-induced intestinal inflammation model in mice. Yoghurt was able to attenuate the symptoms of acute inflammation by reducing inflammatory cytokines, and increasing regulatory cytokine IL-10-producing cells, leading to desirable changes of the intestinal microbiota. It was demonstrated, by using murine models, that the consumption of fermented milks can modulate the immune system and can maintain it in a state of surveillance, which could affront different pathologies such as cancer and intestinal inflammation.
(Online publication June 16 2010)
http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=7837748
